MSD Manual

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Acute Interstitial Pneumonia

(Accelerated Interstitial Pneumonia; Hamman-Rich Syndrome)

By

Joyce Lee

, MD, MAS, University of Colorado School of Medicine

Reviewed/Revised Jul 2023
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Acute interstitial pneumonia is an idiopathic interstitial pneumonia that develops suddenly and is severe.

The diagnosis is confirmed when other causes of acute lung injury are excluded and consistent findings are found with computed tomography (CT) and lung biopsy, if done.

Treatment aims to keep the person alive until the disorder resolves. Mechanical ventilation Mechanical Ventilation Mechanical ventilation is use of a machine to aid the movement of air into and out of the lungs. Some people with respiratory failure need a mechanical ventilator (a machine that helps air get... read more is needed if there is respiratory failure. Corticosteroids are generally used, but it is not clear whether they are effective.

More than 50% of affected people die within 6 months, usually as a result of respiratory failure. In people who survive, lung function usually improves with time. However, the disease may recur.

NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
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