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Biology of the Blood Vessels


Jessica I. Gupta

, MD, University of Michigan Health;

Michael J. Shea

, MD, Michigan Medicine at the University of Michigan

Reviewed/Revised May 2022 | Modified Sep 2022
Topic Resources

The blood vessels consist of

  • Arteries

  • Arterioles

  • Capillaries

  • Venules

  • Veins

All blood is carried in these vessels.

Blood Vessels: Circulating the Blood

Blood travels from the heart in arteries, which branch into smaller and smaller vessels, eventually becoming arterioles. Arterioles connect with even smaller blood vessels called capillaries. Through the thin walls of the capillaries, oxygen and nutrients pass from blood into tissues, and waste products pass from tissues into blood. From the capillaries, blood passes into venules, then into veins to return to the heart.

Arteries and arterioles have relatively thick muscular walls because blood pressure in them is high and because they must adjust their diameter to maintain blood pressure and to control blood flow. Veins and venules have much thinner, less muscular walls than arteries and arterioles, largely because the pressure in veins and venules is much lower. Veins may dilate to accommodate increased blood volume.

Blood Vessels: Circulating the Blood

If a blood vessel breaks, tears, or is cut, blood leaks out, causing bleeding. Blood may flow out of the body, as external bleeding, or it may flow into the spaces around organs or directly into organs, as internal bleeding.

Arteries and arterioles

The arteries, which are strong, flexible, and resilient, carry blood away from the heart and bear the highest blood pressures. Because arteries are elastic, they narrow (recoil) passively when the heart is relaxing between beats and thus help maintain blood pressure The Body's Control of Blood Pressure High blood pressure (hypertension) is persistently high pressure in the arteries. Often no cause for high blood pressure can be identified, but sometimes it occurs as a result of an underlying... read more The Body's Control of Blood Pressure . The arteries branch into smaller and smaller vessels, eventually becoming very small vessels called arterioles. Arteries and arterioles have muscular walls that can adjust their diameter to increase or decrease blood flow to a particular part of the body.

Blood Vessels


Capillaries are tiny, extremely thin-walled vessels that act as a bridge between arteries (which carry blood away from the heart) and veins (which carry blood back to the heart). The thin walls of the capillaries allow oxygen and nutrients to pass from the blood into tissues and allow waste products to pass from tissues into the blood.

Venules and veins

Blood flows from the capillaries into very small veins called venules, then into the veins that lead back to the heart. Veins have much thinner walls than do arteries, largely because the pressure in veins is so much lower. Veins can widen (dilate) as the amount of fluid in them increases. Some veins, particularly veins in the legs, have valves in them, to prevent blood from flowing backward. When these valves leak, the backflow of blood can cause the veins to stretch and become elongated and convoluted (tortuous). Stretched, tortuous veins near the body's surface are called varicose veins Varicose Veins Varicose veins are abnormally enlarged superficial veins in the legs. Varicose veins may cause your legs to ache, itch, and feel tired. Doctors can detect varicose veins by examining the skin... read more Varicose Veins .

Names of blood vessels

Blood vessels are arranged about the same way in people. Major vessels are given names that are typically based on what organ they connect to or where they are located. For example, the renal arteries and veins connect to the kidneys, and the subclavian arteries and veins are below the clavicle (collarbone).

Blood Vessels and Lymph Nodes

Blood Vessels and Lymph Nodes
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