Small-Intestine Tumors That Are Noncancerous

ByAnthony Villano, MD, Fox Chase Cancer Center
Reviewed/Revised Oct 2023
VIEW PROFESSIONAL VERSION

Most tumors of the small intestine are noncancerous (benign). These include tumors of fat cells (lipomas), nerve cells (neurofibromas), connective tissue cells (fibromas), and muscle cells (leiomyomas).

Symptoms of Noncancerous Small-Intestine Tumors

Most noncancerous tumors of the small intestine do not cause symptoms. However, larger ones may cause pain, blood in the stool, a partial or complete intestinal obstruction, or intestinal strangulation if one part of the intestine telescopes into an adjacent part (a condition called intussusception). Some noncancerous tumors secrete hormones (see Gastrinoma) or hormonelike substances (see Vipoma) that can cause symptoms such as diarrhea or flushing.

Diagnosis of Noncancerous Small-Intestine Tumors

  • Enteroclysis

  • Endoscopy

  • Video capsule endoscopy

Doctors typically do enteroclysis. In this procedure, a large amount of barium liquid is inserted through a tube in the nose and x-rays are taken as the barium moves through the digestive tract. Sometimes this procedure is done with a computed tomography (CT) scan instead of plain x-rays, in which case the person can just drink the barium rather than having a tube put through their nose.

For endoscopy, a doctor passes an endoscope (a flexible viewing tube) through the mouth and down to the duodenum and part of the jejunum (the upper and middle sections of the small intestine) to locate the tumor and do a biopsy (remove a tissue sample for examination under a microscope). A doctor can sometimes see tumors of the ileum (the lower section of the small intestine) by passing a colonoscope (an endoscope used to view the lower part of the digestive tract) through the anus, through the entire large intestine, and up into the ileum.

A wireless battery-powered capsule that contains one or two small cameras (video capsule endoscopy) can be swallowed to take pictures of tumors of the small intestine.

Sometimes exploratory surgery is needed to identify a tumor in the small intestine.

Treatment of Noncancerous Small-Intestine Tumors

  • Various removal methods

Small noncancerous growths may be destroyed by treatments that are done at the same time as endoscopy. These treatments include applying an electrical current (electrocautery) or heat (thermal obliteration) directly to the growth or directing a high-energy beam of light at the growth (laser phototherapy).

For large growths, surgery may be needed.

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